Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis.
...Published in Nature Biotechnology
The diversity of autoimmune responses poses a formidable challenge to the development of antigen-specific tolerizing therapy. We developed myelin proteome microarrays to profile the evolution of autoantibody responses in experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis (MS). Increased diversity of autoantibody respo...
